Does Modafinil Cause Tolerance? Signs, Risks, and How to Manage It
Modafinil is widely prescribed to improve alertness and reduce excessive daytime sleepiness in conditions such as narcolepsy, obstructive sleep apnea, and shift work disorder (U.S. Food and Drug Administration [FDA], 2015). While many patients benefit from its wakefulness-promoting effects, some notice that the medication becomes less effective over time — raising the question of tolerance….
